Investigators – University of Copenhagen

Investigators

Guillaume Amouroux, Ph.D., Postdoctoral Fellow
Faculty of Pharmaceutical Sciences
The University of British Columbia

 

I am a biologist specialized in anti-cancer drug testing. My research comprises the evaluation of radiolabeled biomolecules, especially peptides and proteins, by quantitative imaging (PET/SPECT/CT) in in vitro and in vivo models (more information).

 

Ditlev Birch, Ph.D., Postdoctoral Fellow

Department of Pharmacy
University of Copenhagen

 

I am a pharmacist specialized in in vitro cell models for studying the epithelial permeation, cellular uptake and cellular distribution of peptide and protein drugs mediated by cell-penetrating peptides. In order to achieve this, I employ cell-based methodologies combined with advanced microscopy and bioanalysis (more information).

Ada-Ioana Bunea, Ph.D., Postdoctoral Fellow

Programmable Phase Optics
DTU Fotonik

My research focus within the project is related to the development of a lab-on-chip system for studying drug-biobarrier interactions with the aid of light-controlled microtools. My background is highly interdisciplinary, extending from cleanroom microfabrication to stem cell culture and differentiation, and encompassing different characterisation techniques (e.g. SEM, XPS, fluorescence microscopy, electrochemical techniques) (more information).

Niels Johan Christensen, Ph.D.,
Postdoctoral Fellow

Department of Chemistry

University of Copenhagen

I am specialized in molecular modeling and computational chemistry. My main focus is to establish in silico models for understanding the interaction between mucus, peptides and excipients (more information).

Manto Chouliara, M.S., Research Assistant

Department of Photonics Engeneering

DTU Photonik

My research focuses on the fabrication of microtools and on their optical manipulation in order to investigate the function of novel excipients at a molecule/DDS-to-single cell level in a dynamic situation (more information).

Ragna Guldsmed Diedrichsen, M.S., Research Assistent

Department of Pharmacy
University of Copenhagen

My research comprises evaluation of transepithelial permeation of therapeutic proteins by employing cell-penetrating peptides and investigation of interactions between the cell-penetrating peptides and therapeutic proteins or the epithelium (more information).

Einstom Engay, Ph.D. Student

Department of Photonics Engeneering

DTU Photonik

My research is on utilizing light-matter interaction to fabricate, functionalize and manipulate tools for in vitro study of drug-barrier interaction in a specialized lab-on-a-chip system, and on using optical characterization techniques to elicit information on the drug-barrier interaction (more information).

Sofie Fogh Hedegaard, Ph.D.,
Postdoctoral Fellow

Department of Pharmacy
University of Copenhagen

My research interest encompasses the vast potentials within drug delivery of biopharmaceuticals. My main expertise is within biophysical investigations of molecular interactions, with a specific focus on membrane interaction of cell-penetrating peptides

 (more information).

Panagiota Kalomoiri, Ph.D Student
Department of Chemistry

University of Copenhagen


My research focuses on chemically modified peptides as potential biopharmaceuticals, for which oral delivery would give important treatment options. I am interested in investigating the interaction and transportation of biopharmaceuticals across mucus and epithelial barriers. My aim is to study the pharmacokinetics by bio-imaging of the biopharmaceuticals. 

Narendra Kumar Mishra, Ph.D.,
Postdoctoral Fellow

Department of Chemistry

University of Copenhagen


In broad outline, my research interest lies in the chemical science domain. Specific area of my research is the chemical modification of proteins with abiotic ligand and followed by self-assembly in presence of divalent and trivalent cations in order to organize tertiary structures to give new, artificial quaternary architectures of proteins.

 

Kathy Saatchi, Ph.D., Senior Research Associate

Faculty of Pharmaceutical Sciences
The University of British Columbia

My research comprises the design of diagnostic, therapeutic or theranostic radiopharmaceuticals. My main expertise is the syntheses and radiolabeling of small and macro (bio)molecules and nanomedicines for imaging by PET/SPECT/CT (more information).

Tanya Saxena, Ph.D. Student

Faculty of Pharmaceutical Sciences
The University of British Columbia

 

My research involves the development and testing of site-directed oral delivery of biomacromolecules in capsules to the intestine. I then investigate the radiolabeled drug moieties by preclinical SPECT/CT imaging to determine their biodistribution and pharmacokinetics (more information).

 

David Schultz, Master Student
Department of Pharmacy
University of Copenhagen

The focus of my research is to generate new data on parameters relevant for the absorption of peptide drugs across the oral mucosa after oral dosing. Specifically, to assess the effect on the mucus layer surface-lining the epithelial membrane during exposure to exogenous compounds like permeation enhancers.